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agate
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Joined: 17 May 2006
Posts: 5694
Location: Oregon
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 Posted: Tue Oct 10, 2006 1:20 pm Post subject: (Abstract) Episodic memory in MS |
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From PubMed, October 10, 2006:
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Rev Neurol (Paris). 2006 Sep;162(8-9):852-857
[Study of episodic memory in multiple sclerosis using the California Verbal Learning Test: the data favour altered encoding.][Article in French]
Defer GL, Daniel F, Marie RM.
UPRES-EA 3917, Service de Neurologie Dejerine, CHU de Caen, 14033 Cedex.
Introduction. Alteration of episodic memory is one of the main cognitive deficits observed in MS patients. Patients and methods. We studied episodic memory in a group of 71 MS patients (37 RR, 34 SP) with the California Verbal Learning test (CVLT). Direct scores and calculated indices from CVLT performances were analyzed in comparison with controls.
RESULTS: We observed a deficit of episodic memory in 69 percent of patients. This deficit was related to an alteration of encoding and retrieval processes. [Although] SP-MS patients' performances were constantly lower than those of RR-MS patients, no significant difference was observed between the two groups.
Significant correlation[s] between the disease duration and CVLT performances were observed for the whole group but not for RR- or SP-MS groups separately, indicating that duration is more important than the phase of the disease in the worsening of memory deficit.
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http://tinyurl.com/qtxsc
Last edited by agate on Tue Oct 10, 2006 11:03 pm; edited 2 times in total |
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lady_express_44
Joined: 22 May 2006
Posts: 1314
Location: Vancouver, Canada
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| Posted: Tue Oct 10, 2006 2:35 pm Post subject: |
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Interesting, but not too suprising I guess.
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Matt
Joined: 21 May 2006
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| Posted: Thu Oct 12, 2006 2:17 pm Post subject: |
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| 69% of patients. That's huge, unfortunately. |
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agate
Site Admin
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Location: Oregon
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| Posted: Thu Oct 12, 2006 2:21 pm Post subject: |
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| A question for those who know statistics: Isn't a group of 71 patients a rather small sample, though? |
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Matt
Joined: 21 May 2006
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| Posted: Thu Oct 12, 2006 2:26 pm Post subject: |
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| There must be some way to do a chi-aquare test to ding out the 95% confidence interval, but I hate chi-square tests, so it's not gonna happen, sorry. |
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Matt
Joined: 21 May 2006
Posts: 961
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| Posted: Thu Oct 12, 2006 2:51 pm Post subject: |
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| Ok...So, I did a chi square. This number predicts that there is greater that a 95% chance that more than 52% have the memory problems GIVEN THE SELECTION CRITERIA, whatever they are. |
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