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agate
Site Admin
Joined: 17 May 2006
Posts: 5694
Location: Oregon
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 Posted: Fri Oct 13, 2006 1:53 pm Post subject: (Abstract) Liver test abnormalities in MS |
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From PubMed, 10/13/06:
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Neurology. 2006 Oct 10;67(7):1291-3.
Liver test abnormalities in multiple sclerosis: findings from placebo-treated patients
Tremlett H, Seemuller S, Zhao Y, Yoshida EM, Oger JD, Petkau J.
Faculty of Medicine, Department of Medicine, Division of Neurology, University of British Columbia, Vancouver, BC, Canada. tremlett@interchange.ubc.ca
The risk of an abnormal liver test in 813 patients with multiple sclerosis or clinically isolated syndrome enrolled in placebo arms of clinical trials was greater than expected for alanine aminotransferase (ALT) (relative risk [RR] 3.7; 95% CI: 2.3 to 6.0) and aspartate aminotransferase (AST) (RR 2.2; 95% CI: 1.3 to 3.6), although not alkaline phosphatase (AP) or total bilirubin, at first presentation.
Abnormal test results were associated with higher body mass index (ALT only), male gender (ALT only), and a relapsing-remitting (vs secondary-progressive) course (ALT and AST only).
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Sweetyhide
Joined: 26 Jun 2006
Posts: 131
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| Posted: Sun Oct 15, 2006 2:00 am Post subject: |
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You know I was looking through my tests (picked up all my records for the Tovaxin trial) and saw where my AST & ALT levels were high. I was wondering why since this was performed before I started MS meds.
I figured it was because I was on a high dose of statin, but it was normal on another test then back up again. I wonder if it's related to exerbations. |
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